Examples Of Highly Flammable Chemicals Used In The Lab

Originally published August 18, 2021 01:25:52 AM, updated August 25, 2021

Working with flammable chemicals is just part of the normal work week  for many Laboratory ManagersOver the course of their career, lab technicians will be exposed to a wide range of flammable chemicals. If chemicals are mishandled or stored incorrectly, they can be hazardous.  

And while most accidents in laboratories happen due to unintentional negligence, the chance for error can be minimised if the right measures are put in placeOne preventative measure that you can be taken to ensure your safety is to keep your flammable chemicals in secure flammable storage cabinets while they are not being used. 

What Are The Dangers Of Working With Flammable Chemicals?

Aside from the risk of combustion — which can lead to injury, death and destruction of property — flammable liquids also present various health hazards beyond burns. Dizziness, asphyxiation or even tremors can be caused by excessive exposure to vapours that are emitted from flammable liquids.   

Preventing Class 3 Flammable Liquids from spilling (1)Flammable Chemicals

To prevent the acute and chronic health hazards associated with flammable liquidsand the risk of fatality, you must first be aware of the dangerous properties of these substances. This will then allow you to devise a strategy to reduce the risks to your team, your lab and your environment.  

In this blog, we look at some examples of highly flammable chemicals that may be found in the laboratory.  


Acetone or propanone is an organic compound and the simplest ketone with a chemical formula of (CH3)2COIt is an important solvent often used as a cleaning agent in laboratories.  

Acetone has other practical uses outside of the confines of the laboratory. Dermatologists use acetone with alcohol to peel off dry skin when treating acne. Because acetone has a very strong ability to dissolve glue, it is used to remove super glue residue from glass and porcelain.   

This flammable substance is colorless and volatile. Acetone has an extremely low flash point of −20 °C, giving it the ability to readily ignite at room temperature.


Acetone Exposure & Poisoning

Acetone exposure can cause both acute and chronic health issues if it is inhaled, ingested or comes into contact with the eyes of the skinAcetone poisoning, while rare, occurs when there’s more acetone in your body than your liver can break down. A laboratory accident or mishandling of acetone can quickly result in a range of serious health issues. 

Symptoms may include: 

  • Lethargy 
  • Slurred speech 
  • Lack of coordination 
  • Headache 
  • Irritation to eyes, nose, throat and lungs 
  • Dizziness 
  • Confusion 
  • Fainting 

Chronic health effects may include: 

  • Damage to kidney, liver and nerves 
  • Birth defects 
  • Reproductive issues 
  • Potential for coma 

HeadacheHealth issues due to Acetone


Benzene is a hydrocarbon, which means that it only comprises of carbon and hydrogen atoms.  

This organic chemical compound’s most common use is as an intermediate when producing other chemicals.  

Benzene is a byproduct of fuel combustion and over half of the benzene produced in the world is used to make ethylbenzene. Ethylbenzene is used to make polymers and plastics. Over 20% of benzene goes into the manufacture of cumene, which is an important component in producing phenol acetone which is then used to make resins and adhesives.  

With a flash point of -11.63 °CBenzene is also highly flammable. 


Symptoms Of Benzene Exposure

If benzene vapours are inhaled or ingested, signs of a health hazard may be apparent within minutes or several hours. 

Signs of benzene exposure include:  

  • Drowsiness 
  • Dizziness 
  • Rapid or irregular heartbeat 
  • Headaches 
  • Confusion 
  • Tremors 
  • Vomiting 
  • Convulsions 

Chronic health effects may include: 

  • Anemia 
  • Immune system issues 
  • Fertility problems 
  • Leukemia 


Methanol is a flammable chemical also referred to as “wood alcohol”. It got its name “wood alcohol” because most of it used to be produced from destructively distilling wood.  

Today, most methanol is produced from a catalytic process involving carbon monoxide, carbon dioxide and hydrogen.  

The primary use of methanol is as a base product for manufacturing chemicals. These chemicals are then used to produce a range of products including plastics, paints and explosives. Methanol can also be utilised as a fuel for some performance vehicles. Many laboratories around Australia and the world use methanol as a solvent.  

Methanol is also a highly flammable chemical with a flash point between 11 and 12 °C.

Symptoms Of Methanol Poisoning

The concerning health effects from methanol poisoning may not be noticed until after an asymptomatic period (1 to 72 hrs). 

Signs may include: 

  • Drowsiness 
  • Reduced consciousness 
  • Headache 
  • Confusion 
  • Nausea 
  • Vomiting 
  • Heart and respiratory failure 
  • Blindness 


Mainly used for industrial purposescyclohexane is a flammable chemical which is used to produce adipic acid and caprolactam — the two products used to produce nylon.  

Cyclohexane is a colorless liquid with a distinct scent. In fact, the strong smell in household detergents comes from cyclohexane. Scanning calorimetry instruments use cyclohexane for calibration. Cyclohexane is a chemical that is commonly utilised in lab processes and it can be found in lab equipment. 

It is also a very flammable liquid with a flash point of -20 °C.

Flash Point

Health Issues Associated With Cyclohexane  

As with any chemical, cyclohexane exposure can be fatal. Acute symptoms can appear quickly and include dizziness and drowsiness. 

What are some of the symptoms of cyclohexane exposure? 

  • Dizziness 
  • Headaches 
  • Drowsiness 
  • Motor changes 
  • Limb weakness 
  • Verbal memory impairment 
  • Risk of fatality 


Also known as alcohol, ethyl alcohol or drinking alcohol, ethanol is a highly flammable liquidMost alcoholic beverages contain a percentage of ethanol. 

It is a volatile and colorless substance with a distinct odor. Its flash point depends on the concentration of ethanol. An extreme example would be pure ethanol which burns at    16.60 °C. 

Ethanol is often used as an antiseptic in hospitals, clinics and homes. As it can effectively kill bacteria and fungi, it is found in medical wipes and sanitisers. Other uses for ethanol include it being used as engine fuel or a fuel additive.  

Ethanol formulaEthanol

Signs Of Over-Exposure To Ethanol

While ethanol is found is everyday household products, the risk of ethanol exposure is a potential hazard for labs.  

Signs of ethanol exposure can include: 

  • Drowsiness 
  • Confusion 
  • Vomiting 
  • Seizures 
  • Slow breathing  
  • Slow responses 
  • Long pauses between breaths  
  • Low body temperature 
  • Bluish or pale skin 


Pentane is an acyclic saturated hydrocarbon that falls into the alkane group. Each pentane molecule contains five carbon atoms, and it exists as three different structural isomers. Pentane is a clear liquid with a mild gasoline-like odour. It is commonly used as a fuel or solventThis chemical can also be found in plastics and in low-temperature thermometers. 

As pentane is relatively inexpensive and evaporate quickly, pentanes are used as solvents. Pentanes can also be used to carry out a process called “liquid chromatography” — which is a laboratory technique for separating mixtures.    

Pentane is a very flammable chemical with a flash point of -49 °C. 

Adverse Health Effects Associated With Pentane

Pentane is a hazardous substance that can cause adverse health effects. Exposure to pentane can occur if it is inhaled, ingested or comes into contact with the eyes or body. 

Symptoms of pentane exposure may include: 

  • Eye and skin irritation 
  • Headaches 
  • Dizziness 
  • Passing out 

Chronic health symptoms include: 

  • Damage to the nervous system 
  • Blisters and skin problems 
  • Pulmonary edema 

How To Reduce Risks Involved With Flammable Chemicals

Safety in Laboratories (AS 2243) is a standard that details the specifications and guidelines for operational safety in laboratories. Section 3 of Part 10 of this standard states that chemical storage cabinets for dangerous goods are designed to protect the contents against damage, provide segregation between incompatible substances, and to contain spills. The storage cabinet should also be engineered to allow at least 10 minutes for escape of persons — or use of firefighting equipment.  

However, to properly protect laboratory staff from the risks of flammable chemicals, a chemical storage cabinet should also be ventilated. Ventilating a chemical storage cabinet prevents the occurrence of dangerous gases from building up within the cabinet. If a cabinet is not ventilated, gases may build up and be released on the unsuspecting laboratory technician when they open the storage cabinet.  

Exposure to these vapours can cause a range of acute and chronic symptoms —— including death. To reduce the risk of exposure, proper ventilation of chemical storage cabinets is required. If you’d like to learn more about the benefits of ventilated dangerous goods storage cabinets, why not download our free eBook by clicking on the image below? 

How to ventilate dangerous goods storage cabinets

Walter Ingles

Walter Ingles Compliance Specialist

Walter is STOREMASTA’s Dangerous Goods Storage Specialist. He helps organisations reduce risk and improve efficiencies in the storage and management of dangerous goods and hazardous chemicals.

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